two.four mya with the emergence of A. microta.[sixty][61] Genome sequencing of the large panda implies that the dietary change might have initiated from the loss of the only real umami taste receptor, encoded through the genes TAS1R1 and TAS1R3 (generally known as T1R1 and T1R3), resulting from two frameshift mutations inside the T1R1 exons.[fifty]

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